Watch Arizona Cardinals at Cleveland Browns: Live Stream, TV Channel, Start Time

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Kyler Murray and the Cardinals are set for a tough Week 6 test, as they travel to face the Browns and Baker Mayfield.
Evan Massey

One of the most anticipated games of Week 6 will be played between the Cardinals and Browns on Sunday afternoon.

How to Watch: Cardinals at Browns

Game Date: Oct. 17, 2021

Game Time: 4:00 p.m. EST

TV: FOX (WXIN-TV – Indianapolis, IN)

Kyler Murray and the Cardinals have been dominant this season and look like a legitimate Super Bowl contender in the NFC. Coming into this game, they hold a 5-0 record and first place in the NFC West division race. Arizona is an extremely good football team on both sides of the ball.

Speaking of Murray, he has also been picking up some hype in the MVP race. He has racked up 1,512 yards, 10 touchdowns and four interceptions while completing a sizzling 75.2% of his passes. Murray has also picked up 110 yards and three touchdowns on the ground.

On the other side of the field, the Browns are still looking to find their groove and heat up. Baker Mayfield has been receiving a lot of criticism, but the Browns still have a 3-2 record. A win this week over the undefeated Cardinals would quiet most of the critics.

For the Browns, Mayfield has not been able to get going consistently yet. He has completed 66.9% of his passes for 1,240 yards, four touchdowns and two interceptions. If Mayfield can find a rhythm, the Browns will be just fine.

Kyler Murray and the Cardinals have been dominant this season and look like a legitimate Super Bowl contender in the NFC. Coming into this game, they hold a 5-0 record and first place in the NFC West division race. Arizona is an extremely good football team on both sides of the ball.

Speaking of Murray, he has also been picking up some hype in the MVP race. He has racked up 1,512 yards, 10 touchdowns and four interceptions, while completing a sizzling 75.2% of his passes. Murray has also picked up 110 yards and three touchdowns on the ground.

On the other side of the field, the Browns are still looking to find their groove and heat up. Baker Mayfield has been receiving a lot of criticism, but the Browns still have a 3-2 record. A win this week over the undefeated Cardinals would quiet most of the critics.

For the Browns, Mayfield has not been able to get going consistently yet. He has completed 66.9% of his passes for 1,240 yards, four touchdowns and two interceptions. If Mayfield can find a rhythm, the Browns will be just fine.

 How to watch, listen, stream,  announcers and more

Week 6 of the NFL is already in full swing as a tight contest across the pond went down to the wire.

Kicking things off, Trevor Lawrence and the Jacksonville Jaguars broke the franchise’s 20-game losing streak, beating the Miami Dolphins 23-20 at London’s Tottenham Hotspur Stadium as part of the NFL’s International Series.

In the early window, Justin Fields and the Chicago Bears host Aaron Rodgers and the Green Bay Packers in the Windy City, and the Los Angeles Rams are in the Big Apple to take on Daniel Jones and the New York Giants.

Meanwhile, the Kansas City Chiefs (2-3) hope to get back on track against the Washington Football Team after falling to last place in the AFC West following a loss to the Buffalo Bills in Week 5.

Later, Kyler Murray and the undefeated Arizona Cardinals are in Cleveland to take on Baker Mayfield and the Browns (4:05 p.m. ET, FOX), and at night, the Pittsburgh Steelers host the Geno Smith-led Seattle Seahawks, who will be without Russell Wilson for the first time in nearly a decade (8:20 p.m. ET, NBC).

Enticing matchup, with both sides peaking at the right time. the Cards have painstakingly crafted a spotless résumé to this point, and the roster has earned every bit of the acclaim it has gotten — but greater pressures typically accompany sustained seasonal perfection. We’re suckers for ball-control run games, and Cleveland is deploying just that, in spades. Swing with the Browns, for one unit.

Those league operatives who craft each annual NFL schedule are pretty sharp. The Bills are a juggernaut — but they’re not necessarily the only one in the league … not to mention that among the worst things an NFL coach can do is permit a hot squad to peak prematurely. Titans coach Mike Vrabel has a tremendous rapport with his players, and the best is almost certainly yet to come. Titans make most of chances, for one unit.

With Arizona Cardinals coach Kliff Kingsbury sidelined for Sunday’s matchup against the Cleveland Browns after testing positive with COVID-19, assistant wide receivers coach Spencer Whipple will assume play-calling duties.

Whipple will be the one communicating with quarterback Kyler Murray, but the Cardinals play calling will be a collaborative effort, according to the NFL Network’s Tom Pelissero.

Run game coordinator/offensive line coach Sean Kugler will still have an input on the rushing attack, with him and Kingsbury normally making the Cardinals’ offensive game plan together. In addition with Kingsbury being out, defensive coordinator Vance Joseph and assistant head coach/special teams coordinator Jeff Rodgers will split head coaching duties.

In his third season in Arizona, Whipple was hired as an offensive quality control coach in 2019. The following year, he was promoted to assistant receivers coach and is in his second season in the role.

Prior to his time with the Cardinals, he spent seven years coaching at the collegiate level. In 2018, Whipple served as the passing game coordinator/quarterbacks coach at Massachusetts.

The Cardinals (5-0) travel to Cleveland to face the Browns (3-2) at 1:05 p.m. on 98.7 FM Arizona’s Sports Station.